Poster - Nk Cells and Infection
نویسندگان
چکیده
Background and aims: Natural killer T (NKT) cells represent a subset of immune cells that share characteristics of the innate and adaptive immunity. Invariant NKT cells recognize glycolipid antigens such as α galactosylceramide (αGalCer) presented by the non classical MHC molecule CD1d. Decreased NKT cell frequencies have been reported in chronically HCV infected patients, however, contradicting reports exist. We therefore aimed to comparatively study NKT cell frequencies and function in people who inject drugs (PWID) with chronic and spontaneously resolved HCV infection.
منابع مشابه
Killer Cell Immunoglobulin-Like Receptors Influence the Innate and Adaptive Immune Responses
Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the unhealthy cells from the healthy ones through an array of cell-surface receptors. Human NK cells use inhibi...
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Natural Killer (NK) cells are the main lymphocyte population expressing P75 B chain of the IL-2 receptor (IL-2R). Consequently, incubation of peripheral blood lymphocytes with IL-2 induce selective activation of NK cells and results in NK activity and generation of Lymphokine activated killer (LAK) cells activity and proliferation. One of the early events during IL-2 activation of peripheral bl...
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